Endocrine Abstracts

Introduction: Hypogonadotropic hypogonadism is the cause of sexual deficiency, sometimes difficult to differentiate from constitutional growth delay (CGD).Clinical case: A 19-year-old male consulting endocrinology for delayed puberty. Pointed to, at 13 years of age, as having had CGD. His medical report include a viral meningitis at 8 years of age and anosmia since 3 years of age. He expressed lack of sexual desire and concern about the size of his genit...

Introduction: Hypocalcaemia is present in half of the patients with 22q11.2 deletion syndrome (DiGeorge-velocardiofacial syndrome). Most of these cases are diagnosed during childhood.Case report: A 56-year-old man was evaluated for symptomatic hypocalcaemia after undergoing a left nephrectomy because of renal tumour. He had paraesthesia around his mouth and hands and Trousseau’s sign. His past medical history included high blood pressure, type 2 dia...

Introduction: 46,XX testicular disorder of sex development (DSD) is a rare syndrome, which is characterized by a female karyotype in discordance with a male phenotype. It is presented with primary hypogonadism, gynecomastia and infertility. About 80–90% of 46,XX testicular DSD cases are positive for SRY gene. Appearance of external genitalia and masculinization are usually normal in 46,XX SRY-positive casesClinical case: A 41-year-old male came with...

Introduction: Cardiovascular disease is present in up to 60% of patients diagnosed of acromegaly and is responsible of the major related morbidity and mortality.Case report: A 79-year-old-woman with previous history of diabetes mellitus and hypertension was admitted for acute pulmonary edema. Transthoracic echocardiogram showed a severe left ventricular dysfunction with an ejection fraction of 20%, dilated left ventricle and left atrium with a moderate m...

Introduction: Primary aldosteronism (PA) is the most common cause of secondary hypertension (5–10%) and it is underdiagnosed. Less than 50% of patients with PA have hypokalemia. The tests for determinate subtype of PA are cross-sectional imaging (adrenal CT or MRI) and adrenal vein sampling (AVS). The AVS seems to be important to direct appropriate therapy and surgery is the preferred treatment for patients with unilateral disease.Material and metho...